Sacubitril and Valsartan Tablets

963.00 INR/Box

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Product Details:

Solubility Practically insoluble in water
Appearance Yellow oval-shaped coated tablets
Suitable For Adults
Assay Each tablet contains Sacubitril 24 mg/49 mg, Valsartan 26 mg/51 mg, or as specified
HS Code 30049099
CAS No 149690-05-1 (Sacubitril), 137862-53-4 (Valsartan)
Purity >99% (per tablet analysis)
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Sacubitril and Valsartan Tablets Price And Quantity

Price Range 554.00 - 963.00 INR/Box
Minimum Order Quantity 100000 Tablet
Price 963.00 INR/Box

Sacubitril and Valsartan Tablets Product Specifications

Suitable For Adults
Appearance Yellow oval-shaped coated tablets
HS Code 30049099
Assay Each tablet contains Sacubitril 24 mg/49 mg, Valsartan 26 mg/51 mg, or as specified
Ingredients Sacubitril, Valsartan, Excipients
Feature Combination of Sacubitril and Valsartan, Brand Equivalent: Entresto
Solubility Practically insoluble in water
CAS No 149690-05-1 (Sacubitril), 137862-53-4 (Valsartan)
Type Cardiovascular medication
Storage Instructions Store below 30C, protect from moisture
Melting Point Sacubitril: 137-140C; Valsartan: 100-105C
Pacakaging (Quantity Per Box) 28 tablets
Molecular Formula Sacubitril: C24H29NO5; Valsartan: C24H29N5O3
Dosage Guidelines As directed by physician
Purity >99% (per tablet analysis)
Shelf Life 24-36 months
Acid Value Not applicable (pharmaceutical product)
Physical Form Tablets
Refractive Rate Not applicable (solid tablet form)

Warning & Precautions Not to be used in pregnancy, history of angioedema, or with concomitant ACE inhibitors
Inactive Ingredients Cellulose, lactose monohydrate, magnesium stearate, povidone, crospovidone, sodium stearyl fumarate
Regulatory Approval WHO GMP, ISO certified
Tablet Strengths Available 24mg/26mg, 49mg/51mg, 97mg/103mg (Sacubitril/Valsartan)
Brand Name Sacubitril and Valsartan Tablets
Identification Marking May contain debossed code for strength
Therapeutic Class Antihypertensive, Heart failure treatment
Release Type Film-coated, immediate release
Marketed By Available via hospital and retail pharmacies
Packaging Type Alu-Alu blister strips
Tablet Size Approx. 10 x 5 mm (oval)
Usage For the treatment of chronic heart failure (NYHA class II-IV) in adults
Color Light yellow to yellow
Route of Administration Oral

Sacubitril and Valsartan Tablets Trade Information

FOB Port MUMBAI
Supply Ability 10000 Tablet Per Year
Delivery Time 01 Week
Sample Available Yes
Sample Policy Free samples available with shipping and taxes paid by the buyer
Packaging Details 10X2X14 TAB (ALU-ALU)
Certifications WHO-GMP

Product Description

SACUBITRIL; VALSARTAN (sak UE bi tril; val SAR tan) is a combination of a neprilysin inhibitor and a an angiotensin II receptor blocker. It treats heart failure. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

How the Combination Works

Sacubitril and Valsartan work synergistically to improve heart efficiency. Sacubitril enhances the levels of beneficial peptides by inhibiting their breakdown, while Valsartan blocks angiotensin II receptors, lowering blood pressure and reducing strain on the heart. Together, they offer holistic management for patients with chronic heart failure.

Therapeutic Benefits

Patients taking this medication often experience a reduction in heart failure symptoms, such as shortness of breath and swelling. Clinical studies have demonstrated that this combination therapy can decrease the risk of cardiovascular death and heart failure hospitalizations compared to other standard treatments, offering improved quality of life.

Practical Usage and Dosage

Sacubitril and Valsartan Tablets must be taken orally as prescribed by a healthcare professional. Dosage adjustments are personalized based on individual response and medical condition. It is important to follow the physician's guidance and not to use these tablets alongside ACE inhibitors or during pregnancy due to specific safety considerations.

FAQ's of Sacubitril and Valsartan Tablets:

Q: How should Sacubitril and Valsartan Tablets be taken for heart failure?

A: Sacubitril and Valsartan Tablets are meant for oral administration and should be taken exactly as directed by your physician, typically twice daily. Swallow the tablet with water, and do not crush or split it. Follow the prescribed dosage and schedule to achieve the best therapeutic effect.

Q: What conditions are Sacubitril and Valsartan Tablets indicated for?

A: These tablets are indicated for the treatment of chronic heart failure in adults, particularly for those classified as NYHA class II-IV. The combination helps manage symptoms and reduces the risk of hospitalization and cardiovascular-related complications.

Q: When should Sacubitril and Valsartan not be used?

A: This medication should not be used in patients with a history of angioedema related to previous ACE inhibitor or ARB therapy, pregnant women, or those taking ACE inhibitors concomitantly. Consultation with a healthcare professional is important before starting this medication.

Q: Where can I purchase Sacubitril and Valsartan Tablets?

A: The tablets are available via hospital and retail pharmacies and can be procured throughout India from authorized suppliers, distributors, or wholesalers. Always ensure your purchase is from trusted, regulated outlets to guarantee authenticity.

Q: What are the potential benefits of using Sacubitril and Valsartan for chronic heart failure?

A: The main benefits include improved heart function, reduced symptoms such as fatigue and fluid retention, and a lowered risk of cardiovascular-related hospitalization or death. This combination therapy has shown significant efficacy over traditional heart failure medications.

Q: How do I store Sacubitril and Valsartan Tablets correctly?

A: Store the tablets below 30C and protect them from moisture. Keep the medication in its original Alu-Alu blister packaging until use and ensure it is kept out of reach of children.

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