Imipenem And Cilastatin Injection

2100.00 INR/Vial

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Product Details:

Dosage Form Injection
Life Span 24 months from the date of manufacture
Salt Composition Imipenem (500 mg) + Cilastatin (500 mg)
Brand Name Custom branding as per manufacturer
Origin of Medicine India
Packaging Type Glass Vial with Flip-Off Seal
Pacakaging (Quantity Per Box) 1 vial per box
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Imipenem And Cilastatin Injection Price And Quantity

Minimum Order Quantity 1000 Vial
Price 2100.00 INR/Vial

Appearance White to pale yellow lyophilized powder
Contraindications Hypersensitivity to -lactam antibiotics, history of severe allergic reaction
Reconstitution Volume 10-100 ml, depending on dose
Reconstitution Fluid Sterile Water for Injection
Route of Administration Intravenous (IV) infusion
Prescription Requirement Yes, under medical supervision
Shelf Stability After Reconstitution Use immediately; stable for up to 4 hours at room temperature, 24 hours refrigerated
Common Side Effects Nausea, vomiting, rash, diarrhea, local infusion site reaction
Mechanism of Action Imipenem inhibits bacterial cell wall synthesis; Cilastatin inhibits renal metabolism of Imipenem

Imipenem And Cilastatin Injection Product Specifications

Dosage As directed by physician (typically 250 mg to 1 gm every 6 to 8 hours)
Indication Complicated infections of the lung, urinary tract, abdomen, skin, and joints
Physical Form Lyophilized Powder
Storage Instructions Store below 25C, protect from light and moisture
Drug Type Prescription Only Medicine
Recommended For Serious bacterial infections in adults and children
Brand Name Custom branding as per manufacturer
Function Antibacterial, broad-spectrum antibiotic therapy
Pacakaging (Quantity Per Box) 1 vial per box
Dosage Guidelines Administer via intravenous infusion only
Origin of Medicine India
Packaging Type Glass Vial with Flip-Off Seal
Suitable For Adults and Pediatric use (as advised by physician)
Ingredients Imipenem and Cilastatin Sodium
Dosage Form Injection
Salt Composition Imipenem (500 mg) + Cilastatin (500 mg)
Life Span 24 months from the date of manufacture
Quantity 500 mg/500 mg per vial

Appearance White to pale yellow lyophilized powder
Contraindications Hypersensitivity to -lactam antibiotics, history of severe allergic reaction
Reconstitution Volume 10-100 ml, depending on dose
Reconstitution Fluid Sterile Water for Injection
Route of Administration Intravenous (IV) infusion
Prescription Requirement Yes, under medical supervision
Shelf Stability After Reconstitution Use immediately; stable for up to 4 hours at room temperature, 24 hours refrigerated
Common Side Effects Nausea, vomiting, rash, diarrhea, local infusion site reaction
Mechanism of Action Imipenem inhibits bacterial cell wall synthesis; Cilastatin inhibits renal metabolism of Imipenem

Imipenem And Cilastatin Injection Trade Information

FOB Port MUMBAI
Supply Ability 10000 Vial Per Day
Delivery Time 01 Week
Sample Available Yes
Sample Policy Free samples available with shipping and taxes paid by the buyer
Packaging Details 10X1X1GM VIAL
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
Certifications WHO-GMP

Product Description

Imipenem and cilastatin injection is used to treat certain serious infections that are caused by bacteria, including endocarditis (infection of the heart lining and valves) and respiratory tract (including pneumonia), urinary tract, abdominal (stomach area), gynecological, blood, skin, bone, and joint infections.

Efficient Treatment for Severe Infections

This injection is specially formulated for complicated bacterial infections that are either hospital-acquired or have not responded to standard antibiotics. With a combination of Imipenem and Cilastatin, it delivers a dual-action approach by targeting a wide range of bacteria and ensuring maximum drug efficacy in the body.

Simple Reconstitution and Administration

Supplied as a sterile lyophilized powder in vials, the product is easy to reconstitute using sterile water for injection. It is administered via intravenous (IV) infusion, ensuring fast distribution and rapid onset of action against harmful bacteria. Healthcare professionals should always supervise preparation and infusion.

Reliable Stability and Safety Profile

Once reconstituted, the solution maintains its stability for up to 4 hours at room temperature and 24 hours when refrigerated. Careful storage below 25C and protection from light and moisture preserve the medication's integrity. The product is suitable for both adult and pediatric patients under strict medical guidance.

FAQ's of Imipenem And Cilastatin Injection:

Q: How should Imipenem and Cilastatin Injection be administered?

A: This medication is intended for intravenous (IV) infusion only. After reconstituting the lyophilized powder with sterile water for injection (10-100 ml as per dose), it should be infused into a vein over a prescribed period by a healthcare professional.

Q: What is the primary benefit of using Imipenem and Cilastatin together?

A: Imipenem acts as a powerful antibiotic against a broad range of bacteria, while Cilastatin prevents its breakdown in the kidneys, allowing higher and prolonged concentrations in the body for more effective treatment of severe infections.

Q: When should the reconstituted solution be used, and how long is it stable?

A: The reconstituted solution should be used immediately for best results. At room temperature, it remains stable for up to 4 hours, and if refrigerated, up to 24 hours.

Q: What types of infections is this injection recommended for?

A: Imipenem and Cilastatin Injection is recommended for complicated infections, such as those involving the lungs, urinary tract, abdomen, skin, or joints, especially when caused by bacteria unresponsive to other treatments.

Q: Who should not use Imipenem and Cilastatin Injection?

A: This medication should not be used by individuals with a known hypersensitivity to -lactam antibiotics or who have a history of severe allergic reactions to similar drugs. Always consult your physician before use.

Q: What are the common side effects of this injection?

A: Possible side effects include nausea, vomiting, diarrhea, rash, and local infusion site reactions. Inform your healthcare provider if you experience any unusual or severe symptoms.

Q: Where should this medicine be stored, and how is it packaged?

A: Store each glass vial below 25C, protected from light and moisture. The product is packaged as one vial per box and is intended for use under strict medical supervision.

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