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Zoledronic acid 5mg injection

Zoledronic acid 5mg injection

Product Details:

  • Formulations Type Injectables
  • Formulations Form Liquid
  • Gender/Age Group Adult
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Product Specifications

  • Injectables
  • Liquid
  • Adult

Trade Information

  • Cash on Delivery (COD), Cash Advance (CA), Delivery Point (DP), Western Union
  • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
  • All India

Product Description

Zoledronic acid (INN) or zoledronate is a bisphosphonate drug given intravenously to treat some bone diseases. It is sold under many trade names worldwide.[1]

Mechanism of action

Zoledronic acid slows down bone resorption, allowing the bone-forming cells time to rebuild normal bone and allowing bone remodeling.[2]

Medical uses

Bone complications of cancer

Zometa is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer, as well as for treating osteoporosis.[3] It can also be used to treat hypercalcemia of malignancy and can be helpful for treating pain from bone metastases.[4]

It can be administered at home rather than in hospital. Such administration has shown safety and quality-of-life benefits in breast cancer patients with bone metastases.[5]

Osteoporosis

Marketed as Aclasta (in Australia) or Reclast (in the US), zoledronic acid may be given as a 5 mg infusion once per year for treatment of osteoporosis in men and post-menopausal women at increased risk of fracture.[medical citation needed]

In 2007, the U.S. Food and Drug Administration (FDA) also approved Reclast for the treatment of postmenopausal osteoporosis.[medical citation needed]

Paget's disease

As Reclast a single dose of 5 mg is used for the treatment of Paget's disease.[medical citation needed][6]


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